Staff at EMBL
Dr. Philip Avner
Head of Outstation and Senior Scientist
Avner Group
EMBL Monterotondo, Adriano Buzzati-Traverso Campus, Via Ramarini 32, 00016 Monterotondo, Italy
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Biography
PhD in yeast genetics, University of Warwick.
CNRS Director of Research.
Head of the Mouse Molecular Genetics Unit at the Institut Pasteur 1990-2011.
Head of the Developmental Biology Department at the Institut Pasteur 2006-2011.
Head of EMBL Monterotondo since 2012.
Publications
The coupling of X-chromosome inactivation to pluripotency. Deuve, J.L. & Avner, P. Annu Rev Cell Dev Biol. 2011 Nov 10;27:611-29. Epub 2011 Jul 29. PubMed
The demoiselle of X-inactivation: 50 years old and as trendy and mesmerising as ever. Morey, C. & Avner, P. PLoS Genet. 2011 Jul;7(7):e1002212. Epub 2011 Jul 21. PubMed
New lessons from random X-chromosome inactivation in the mouse. Clerc, P. & Avner, P. J Mol Biol. 2011 May 27;409(1):62-9. Epub 2011 Feb 15. PubMed
Interaction between nucleosome assembly protein 1-like family members. Attia, M., Forster, A., Rachez, C., Freemont, P., Avner, P. & Rogner, U.C. J Mol Biol. 2011 Apr 15;407(5):647-60. Epub 2011 Feb 17. PubMed
Ftx is a non-coding RNA which affects Xist expression and chromatin structure within the X-inactivation center region. Chureau, C., Chantalat, S., Romito, A., Galvani, A., Duret, L., Avner, P. & Rougeulle, C. Hum Mol Genet. 2011 Feb 15;20(4):705-18. Epub 2010 Nov 30. PubMed
Molecular coupling of Tsix regulation and pluripotency. Navarro, P., Oldfield, A., Legoupi, J., Festuccia, N., Dubois, A., Attia, M., Schoorlemmer, J., Rougeulle, C., Chambers, I. & Avner, P. Nature. 2010 Nov 18;468(7322):457-60. PubMed
Inhibition of type 1 diabetes by upregulation of the circadian rhythm-related aryl hydrocarbon receptor nuclear translocator-like 2. He, C.X., Prevot, N., Boitard, C., Avner, P. & Rogner, U.C. Immunogenetics. 2010 Sep;62(9):585-92. Epub 2010 Jul 30. PubMed
LINE-1 activity in facultative heterochromatin formation during X chromosome inactivation. Chow, J.C., Ciaudo, C., Fazzari, M.J., Mise, N., Servant, N., Glass, J.L., Attreed, M., Avner, P., Wutz, A., Barillot, E., Greally, J.M., Voinnet, O. & Heard, E. Cell. 2010 Jun 11;141(6):956-69. PubMed
2-D structure of the A region of Xist RNA and its implication for PRC2 association. Maenner, S., Blaud, M., Fouillen, L., Savoye, A., Marchand, V., Dubois, A., Sanglier-Cianferani, S., Van Dorsselaer, A., Clerc, P., Avner, P., Visvikis, A. & Branlant, C. PLoS Biol. 2010 Jan;8(1):e1000276. Epub 2010 Jan 5. PubMed
An embryonic story : Laws and orders governing Xist. Navarro P and Avner P. (2010) Invited review in Bioessays, 32: 581-588.
A role for non-coding Tsix transcription in partitioning chromatin domains within the mouse X-inactivation centre. Navarro, P., Chantalat, S., Foglio, M., Chureau, C., Vigneau, S., Clerc, P., Avner, P. & Rougeulle, C. Epigenetics Chromatin. 2009 Jul 20;2(1):8. PubMed
Molecular coupling of Xist regulation and pluripotency. Navarro, P., Chambers, I., Karwacki-Neisius, V., Chureau, C., Morey, C., Rougeulle, C. & Avner, P. Science. 2008 Sep 19;321(5896):1693-5. PubMed
Influence of a non-NK complex region of chromosome 6 on CD4+ invariant NK T cell homeostasis. Vallois, D., Gagnerault, M.C., Avner, P., Rogner, U.C., Boitard, C., Benlagha, K., Herbelin, A. & Lepault, F. J Immunol. 2008 Aug 1;181(3):1753-9. PubMed
The type 1 diabetes locus Idd6 controls TLR1 expression. Vallois, D., Grimm, C.H., Avner, P., Boitard, C. & Rogner, U.C. J Immunol. 2007 Sep 15;179(6):3896-903. PubMed
Nap1l2 promotes histone acetylation activity during neuronal differentiation. Attia, M., Rachez, C., De Pauw, A., Avner, P. & Rogner, U.C. Mol Cell Biol. 2007 Sep;27(17):6093-102. Epub 2007 Jun 25. PubMed
The Xist RNA gene evolved in eutherians by pseudogenization of a protein-coding gene. Duret, L., Chureau, C., Samain, S., Weissenbach, J. & Avner, P. Science. 2006 Jun 16;312(5780):1653-5. PubMed
