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Staff at EMBL

Dr. Christophe Lancrin

Group Leader
Lancrin Group Joint appointment: Developmental Biology Unit

EMBL Monterotondo, Adriano Buzzati-Traverso Campus, Via Ramarini 32, 00016 Monterotondo, Italy

E-mail: send a mail


PhD 2003, Université Pierre et Marie Curie (Paris VI), Paris, France.
Postdoctoral research at the Paterson Institute for Cancer Research, Manchester, United Kingdom.
Group Leader at EMBL since January 2011.


GFI1 and GFI1B control the loss of endothelial identity of hemogenic endothelium during hematopoietic commitment. Lancrin, C., Mazan, M., Stefanska, M., Patel, R., Lichtinger, M., Costa, G., Vargel, O., Wilson, N.K., Moroy, T., Bonifer, C., Gottgens, B., Kouskoff, V. & Lacaud, G. Blood. 2012 Jul 12;120(2):314-22. doi: 10.1182/blood-2011-10-386094. Epub 2012Jun 5. Europe PMC

Identification and characterization of a novel transcriptional target of RUNX1/AML1 at the onset of hematopoietic development. Ferreras, C., Lancrin, C., Lie-A-Ling, M., Kouskoff, V. & Lacaud, G. Blood. 2011 Jul 21;118(3):594-7. doi: 10.1182/blood-2010-06-294124. Epub 2011 Apr15. Europe PMC

The sequential expression of CD40 and Icam2 defines progressive steps in the formation of blood precursors from the mesoderm germ layer. Pearson, S., Lancrin, C., Lacaud, G. & Kouskoff, V. Stem Cells. 2010 Jun;28(6):1089-98. Europe PMC

Blood cell generation from the hemangioblast. Lancrin, C., Sroczynska, P., Serrano, A.G., Gandillet, A., Ferreras, C., Kouskoff, V. & Lacaud, G. J Mol Med. 2010 Feb;88(2):167-72. Epub 2009 Oct 25. Europe PMC

The differential activities of Runx1 promoters define milestones during embryonic hematopoiesis. Sroczynska, P., Lancrin, C., Kouskoff, V. & Lacaud, G. Blood. 2009 Dec 17;114(26):5279-89. Epub 2009 Oct 26. Europe PMC

Early chromatin unfolding by RUNX1: a molecular explanation for differential requirements during specification versus maintenance of the hematopoietic gene expression program. Hoogenkamp, M.*, Lichtinger, M.*, Krysinska, H.*, Lancrin, C.*, Clarke, D., Williamson, A., Mazzarella, L., Ingram, R., Jorgensen, H., Fisher, A., Tenen, D.G., Kouskoff, V., Lacaud, G. & Bonifer, C. Blood. 2009 Jul 9;114(2):299-309. Epub 2009 Apr 1.
* These authors contributed equally to this study. Europe PMC

The haemangioblast generates haematopoietic cells through a haemogenic endothelium stage. Lancrin, C., Sroczynska, P., Stephenson, C., Allen, T., Kouskoff, V. & Lacaud, G. Nature. 2009 Feb 12;457(7231):892-5. Epub 2009 Jan 28. Europe PMC

Extrathymic hemopoietic progenitors committed to T cell differentiation in the adult mouse. Arcangeli, M.L., Lancrin, C., Lambolez, F., Cordier, C., Schneider, E., Rocha, B. & Ezine, S. J Immunol. 2005 Feb 15;174(4):1980-8. Europe PMC

Major T cell progenitor activity in bone marrow-derived spleen colonies. Lancrin, C., Schneider, E., Lambolez, F., Arcangeli, M.L., Garcia-Cordier, C., Rocha, B. & Ezine, S. J Exp Med. 2002 Apr 1;195(7):919-29. Europe PMC