Services
With the growth of the EMBL Monterotondo campus both in terms of groups and numbers of staff members working on the campus, we recognized a need for specified services to assist the scientists to better achieve success. We currently host six services: FACS, the Monoclonal Antibody Core Facility, the Mouse Phenotyping Service, the Transgenic Facility, the Gene Expression Service and the Histology Service.
EMBL has always been at the forefront of technology development because of the close collaboration between researchers and engineering staff which allows the development of tools that serve the constantly changing needs of science.
The recently established Flow Cytometry Facility provides equipment access, as well as technical and scientific support to EMBL research groups for the analysis of a variety of mouse models. With more than 10.000 analyses and 400 experiments performed per year, the facility assists scientists at every stage, from project planning and experimental design, to data collection, analysis and publication.
The Monoclonal Antibody Core Facility (MACF) was established to provide a service for EMBL researchers and EMBO Young Investigators, while continuously advancing the technology. Their mission is to quickly produce high-affinity antibodies in a high-throughput manner while concentrating on quality of product and of service. The MACF manages over 200 projects per year with an annual theoretical capacity of up to 400 projects.
The Mouse Phenotyping Service provides centralised support and services to EMBL investigators, developing and studying animal models and their relevance to human diseases.
The Gene Expression Service provides DNA targeting constructs primarily for downstream mice work. This service does not use conventional cloning exercises but rather alters the DNA molecules by homologous recombination (Red/ET recombination).
The Transgenic Facility was established to offer the EMBL institutes and European scientific community the opportunity to expand the research into mouse models. Specific services offered are the production of transgenic mice, rederivations, creation of knock-out mice, and the cryopreservation of new mouse strains.