Hinxton, 3 August 2020 Bagpipe and Pokemon, or how not to name a human gene The human genome harbours about 19 000 protein-coding genes, many of which still have no known function. As scientists unveil the secrets of our DNA, they come across novel genes that they need to refer to using a unique name. The Human Genome Organisation’s Gene Nomenclature Committee (HGNC) at EMBL’s European Bioinformatics Institute (EMBL-EBI) has published an updated set of guidelines in Nature Genetics to help scientists when naming a new gene. This enables researchers, clinicians and patients, charities, the biomedical industry, the media, and the general public to use the same name when referring to a specific gene.
Heidelberg, 31 July 2020 Visualising the cell's molecular machinery in action In a paper published this week in the journal Science, researchers in EMBL's Mahamid group and Juri Rappsilber's lab at Technische Universität Berlin report how they combined three methods to get high-resolution imagery of parts of the cell that had previously only been studied when removed from the cell and observed in isolation.
Hinxton, 30 July 2020 Europe PMC: unlocking the potential of COVID-19 preprints Europe PMC is now indexing full-text preprints related to the COVID-19 pandemic and the SARS-CoV-2 virus, as well as the underlying data. The project will make COVID-19 scientific literature available as fast as possible in a single repository, in a format that allows text mining. Researchers and healthcare professionals will be able to access and reuse preprints more easily, accelerating research into better treatments or a vaccine.
Hamburg, 29 July 2020 EMBL releases online course on solution scattering from biological macromolecules The Svergun group at EMBL Hamburg has released the course ‘Solution Scattering from Biological Macromolecules’ in an online format for the first time. The course explores different aspects of small-angle X-ray scattering (SAXS) for studying the structure of macromolecules.
Heidelberg, 28 July 2020 Understanding chromosome organisation Our cells contain vast amounts of DNA. But the process through which DNA is carefully ordered and compacted has eluded scientists for decades. Now, a team coordinated by EMBL has helped to shed light on the way in which so much DNA is able to fold in such an ordered way.
Hinxton, 27 July 2020 Artificial intelligence finds patterns of mutations and survival in tumour images Researchers from the Gerstung Group at EMBL-EBI have developed an artificial intelligence algorithm that uses computer vision to analyse tissue samples from cancer patients. The algorithm can distinguish between healthy and cancerous tissues, and can also identify patterns DNA and RNA changes in tumours. The scientists generalised their method to 28 cancers, 167 types of mutations and thousands of RNA changes.
Hinxton, 20 July 2020 Unparalleled inventory of the human gut ecosystem Scientists gathered and published over 200 000 genomes from the human gut microbiome. The catalogue reveals that more than 70% of bacterial species in the human gut have never been grown in the lab. This new data resource could be extremely useful to investigate how the bacterial community in the human gut influences human health and disease
Hinxton, 15 July 2020 Funding to predict the risk of infectious disease outbreaks The far-reaching social and economic impact are still difficult to estimate. One of the lessons learned so far is that better surveillance and prediction tools are needed to identify outbreaks earlier and anticipate their impact.