Seminar Colour Guide:              
Career Event
Thursday, 30 September 2021, 11:00Add to calendarCareers & recruiter talk from NovoNordiskJo Billetoft, Stem Cell CMC & Manufacturing Department, DenmarkSofia Håkansson Buch, Stem Cell CMC & Manufacturing Department, DenmarkHost: EMBL Fellows’ Career ServiceVirtual, Virtual
Planetary Biology Lectures
Monday, 18 October 2021, 14:00Add to calendarPlanetary Scale Metabolomics - Linking Chemotypes to EcosystemsDaniel Petras, University of Tübingen, GermanyVirtual, Virtual
Abstract: https://embl-org.zoom.us/j/93608179765?pwd=dU1aTERLdm5YVEl5MlJ4VVJNMGNrQT09 Meeting ID: 936 0817 9765 Passcode: PBLS
Planetary Biology Lectures
Thursday, 18 November 2021, 16:00Add to calendarTo be announcedMark Bailey, UK Centre for Ecology & Hydrology, United KingdomVirtual, Virtual
Abstract: https://embl-org.zoom.us/j/93608179765?pwd=dU1aTERLdm5YVEl5MlJ4VVJNMGNrQT09 Meeting ID: 936 0817 9765 Passcode: PBLS
EMBL - Sapienza Lecture
Friday, 19 November 2021, 11:00Add to calendarTo be announcedAndrew Pospisilik, Van Andel Institute Grand Rapids, MI, USAHost: Mathieu Boulard/Irene BozzoniSapienza Università di Roma - Aula Odeion - Museo dell'Arte Classica - P.le Aldo Moro, 5 - Roma, EMBL Rome
External Faculty Speaker
Friday, 26 November 2021, 11:00Add to calendarTo be announcedMaxim Greenberg, Institut Jacques Monod, Paris, FranceHost: Jamie HackettCNR Seminar Room, EMBL Rome
External Faculty Speaker
Friday, 3 December 2021, 11:00Add to calendarTo be announcedSimona Giunta, Dpt. di Biologia e Biotecnologie Charles Darwin Università di Roma Sapienza Rome, ItalyHost: Mathieu BoulardCNR Seminar Room, EMBL Rome
External Faculty Speaker
Friday, 10 December 2021, 11:00Add to calendarThe Awakening of the 3D GenomeJuanma Vaquerizas, MRC London Institute of Medical Sciences London, United KingdomHost: Ana BoskovicVirtual seminar, EMBL Rome
Abstract: The three-dimensional organisation of the genome plays a fundamental role in the regulation of gene expression. However, despite the recent characterisation of regulators associated to this organisation, we currently lack an understanding of how chromatin conformation is first established during development, and the molecular mechanisms that drive this process. In the first part of my talk, I will focus on recent work in which, using Drosophila as a model system, we investigated chromatin conformation dynamics in embryos at different time points during early embryonic development. Using genetic tools and single-cell technologies, we evaluate the level of heterogeneity in chromatin conformation across different tissues at sub-kilobase resolution. This allows us to unveil that the three-dimensional organisation of chromatin at this developmental stage is likely to serve as an architectural framework to enable transcriptional regulation. In the second part of my talk, I will turn into mammalian early embryonic development. In particular, I will focus on transposable elements, which are highly abundant in eukaryotic genomes and have been recently associated with the process of zygotic genome activation. Using genome-wide chromatin conformation maps, I will show how the Murine Endogenous Retroviral Element (MuERV-L/MERVL) family of transposable elements drives 3D chromatin reorganisation in 2-cell-embryo-like cells as well as in the mouse 2-cell embryo. This reorganisation involves the emergence of hundreds of TAD boundaries across the genome and it is associated to the upregulation of directional transcription from MERVL, which results in the activation of a subset of 2-cell embryo genes. These results have important implications for our understanding of how nuclear organisation emerges during zygotic genome activation in mammals, and how this organisation can be influenced by repetitive elements during early embryonic development.
EMBL Distinguished Visitor Lecture
Friday, 1 April 2022, 10:00Add to calendarTo be announcedAlexander Borst , Max-Planck-Institute of Neurobiology, Martinsried, GermanyHost: Hiroki AsariCNR Seminar Room, EMBL Rome
Tags: Neurobiology
EMBL - Sapienza Lecture
Friday, 29 April 2022, 11:00Add to calendarTo be announcedClaire Wyart, Institut du Cerveau et de la Moelle Epiniere CHU, Paris, FranceHost: Cornelius Gross/Andrea MeleSapienza Università di Roma - Aula Odeion - Museo dell'Arte Classica - P.le Aldo Moro, 5 - Roma, EMBL Rome
Tags: Neurobiology
EMBL Distinguished Visitor Lecture
Friday, 16 September 2022, 15:00Add to calendarTo be announcedMargaret Livingstone, Harvard Medical School, Boston, MA, USAHost: Santiago RompaniCNR Seminar Room, EMBL Rome
Tags: Neurobiology
EMBL - Sapienza Lecture
Friday, 7 October 2022, 11:00Add to calendarTo be announcedTracy Bale, Center for Epigenetic Research in Child Health and Brain Development University of Maryland School of Medicine Baltimore, MD, USAHost: Cornelius Gross and Andrea MeleSapienza Università di Roma - Aula Odeion - Museo dell'Arte Classica - P.le Aldo Moro, 5 - Roma, EMBL Rome
Tags: Neurobiology
EMBL - Sapienza Lecture
Friday, 21 October 2022, 11:00Add to calendarTo be announcedTony Kouzarides , Milner Therapeutics Institute and Gurdon Institute University of Cambridge Cambridge, United KingdomHost: Mathieu Boulard / Irene BozzoniSapienza Università di Roma - Aula Odeion - Museo dell'Arte Classica - P.le Aldo Moro, 5 - Roma, EMBL Rome