EMBL Rome, Adriano Buzzati-Traverso Campus, Via Ramarini 32, 00015 Monterotondo (RM), Italy

Email: christophe.lancrin@embl.it


  • PhD 2003, Université Pierre et Marie Curie (Paris VI), Paris, France.
    Postdoctoral research at the Paterson Institute for Cancer Research, Manchester, United Kingdom.
    Group Leader at EMBL since 2011.


Total: 13 publication(s)


Vargel O, Zhang Y, Kosim K, Ganter K, Foehr S, Mardenborough Y, Shvartsman M, Enright AJ, Krijgsveld J, Lancrin C. (2016)

Activation of the TGF beta pathway impairs endothelial to haematopoietic transition

Sci Rep 6 doi: 10.1038/srep21518
Europe PMC | doi

Thambyrajah R, Mazan M, Patel R, Moignard V, Stefanska M, Marinopoulou E, Li Y, Lancrin C, Clapes T, Möröy T, Robin C, Miller C, Cowley S, Göttgens B, Kouskoff V, Lacaud G. (2016)

GFI1 proteins orchestrate the emergence of haematopoietic stem cells through recruitment of LSD1.

Nat. Cell Biol. 18(1):21-32. doi: 10.1038/ncb3276
Europe PMC | doi


Vargel O, Zhang Y, Collier P, Baying B, Benes V, Lancrin C. (2014)

TGFβ pathway activation blocks the endothelial to hematopoietic transition

Paper presented at the ISEH 43rd Annual Scientific Meeting, Montréal, Canada, 21-24 August 2014.EXP HEMATOL 42(8):S64. doi: 10.1016/j.exphem.2014.07.243
Europe PMC | doi


Lancrin C, Mazan M, Stefanska M, Patel R, Lichtinger M, Costa G, Vargel O, Wilson NK, Möröy T, Bonifer C, Göttgens B, Kouskoff V, Lacaud G. (2012)

GFI1 and GFI1B control the loss of endothelial identity of hemogenic endothelium during hematopoietic commitment

Blood 120(2):314-322. doi: 10.1182/blood-2011-10-386094
Europe PMC | doi


Ferreras C, Lancrin C, Lie-A-Ling M, Kouskoff V, Lacaud G. (2011)

Identification and characterization of a novel transcriptional target of RUNX1/AML1 at the onset of hematopoietic development

Blood 118(3):594-597. doi: 10.1182/blood-2010-06-294124
Europe PMC | doi


Pearson S, Lancrin C, Lacaud G, Kouskoff V. (2010)

The sequential expression of CD40 and Icam2 defines progressive steps in the formation of blood precursors from the mesoderm germ layer

Stem Cells 28(6):1089-1098. doi: 10.1002/stem.434
Europe PMC | doi

Lancrin C, Sroczynska P, Serrano AG, Gandillet A, Ferreras C, Kouskoff V, Lacaud G. (2010)

Blood cell generation from the hemangioblast

J. Mol. Med. 88(2):167-172. doi: 10.1007/s00109-009-0554-0
Europe PMC | doi


Sroczynska P, Lancrin C, Kouskoff V, Lacaud G. (2009)

The differential activities of Runx1 promoters define milestones during embryonic hematopoiesis

Blood 114(26):5279-5289. doi: 10.1182/blood-2009-05-222307
Europe PMC | doi

Hoogenkamp M, Lichtinger M, Krysinska H, Lancrin C, Clarke D, Williamson A, Mazzarella L, Ingram R, Jorgensen H, Fisher A, Tenen DG, Kouskoff V, Lacaud G, Bonifer C. (2009)

Early chromatin unfolding by RUNX1: a molecular explanation for differential requirements during specification versus maintenance of the hematopoietic gene expression program

Blood 114(2):299-309. doi: 10.1182/blood-2008-11-191890
Europe PMC | doi

Lancrin C, Sroczynska P, Stephenson C, Allen T, Kouskoff V, Lacaud G. (2009)

The haemangioblast generates haematopoietic cells through a haemogenic endothelium stage

Nature 457(7231):892-895. doi: 10.1038/nature07679
Europe PMC | doi

Sroczynska P, Lancrin C, Pearson S, Kouskoff V, Lacaud G. (2009)

In vitro differentiation of mouse embryonic stem cells as a model of early hematopoietic development

Methods Mol. Biol. 538:317-334. doi: 10.1007/978-1-59745-418-6_16
Europe PMC | doi


Arcangeli ML, Lancrin C, Lambolez F, Cordier C, Schneider E, Rocha B, Ezine S. (2005)

Extrathymic hemopoietic progenitors committed to T cell differentiation in the adult mouse

J. Immunol. 174(4):1980-1988. doi: 10.4049/jimmunol.174.4.1980
Europe PMC | doi


Lancrin C, Schneider E, Lambolez F, Arcangeli ML, Garcia-Cordier C, Rocha B, Ezine S. (2002)

Major T cell progenitor activity in bone marrow-derived spleen colonies

J. Exp. Med. 195(7):919-929. doi: 10.1084/jem.20011475
Europe PMC | doi